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Quorum-sensing signals indicate that cystic fibrosis lungs are infected with bacterial biofilms

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This study was supported by grants from the Southern China International Cooperation Base for Early Intervention and Functional Rehabilitation of Neurological Diseases (2015B050501003), Guangdong Provincial Engineering Center For Major Neurological Disease Treatment, Guangdong Provincial Translational Medicine Innovation Platform for Diagnosis and Treatment of Major Neurological Disease, Guangdong Provincial Clinical Research Center for Neurological Diseases

Parag Mallick, chief scientist at Nautilus Biotechnology, says he thinks the field is understanding now more than ever that tau is not a single protein that goes up and down. For example, in a single-molecule study that Mallick and his team posted to bioRxiv, researchers identified at least 130 different tau proteoforms in brain organoids and donor tissue